Exceptional mixed-use offering in South Natick with Charles River views and proximity to the historic waterfalls. This distinctive Greek revival-style property combines a renovated residence with long-term professional income, appealing to owner-users, investors, and lifestyle buyers seeking flexibility. The upper levels feature a fully renovated 5-bedroom, 3.5-bath residence with generous living spaces, updated systems, and quality finishes throughout, living like a single-family home with scenic river views. The first-floor professional dental office offers approximately 900 square feet with a 20-year lease, tenant-paid utilities, and stable income in place, with functional space and future upside. Set on approximately 0.52 acres with 9+ off-street parking spaces, this rare commercial/residential property offers lifestyle appeal, income stability, and long-term flexibility in one of South Natick’s most desirable locations